Endocrine Abstracts

IntroductionGrowth hormone deficiency (GHD) is a rare disorder and severe forms of GHD may have a genetic basis. Familial isolated growth hormone deficiency (IGHD) is classified into 4 types, type IA being the most severe form. These patients present with severe growth failure with undetectable growth hormone (GH) concentrations and about 50% tend to develop antibodies on GH treatment.(1, 2, 3) The appearance of anti-GH antibodies may not be a regular fi...